Description
Dosage (Male)
1–2 tablets (10–20 mg) per day
Dosage (Female)
1–2 tablets (10–20 mg) per day
Frequency
Daily (divided doses, fasted)
Dosage Type
Oral Tablet
Active Half-Life
6–8 hours
Post-Cycle PCT
N/A
What is
Yohimbine?
Yohimbine is an indole alkaloid derived from the bark of the Pausinystalia yohimbe tree, native to central and western Africa. As a selective alpha-2 adrenergic receptor antagonist, it works by blocking the receptors responsible for inhibiting fat breakdown. This blockade elevates norepinephrine levels, stimulating lipolysis and mobilizing stored fatty acids as fuel. Yohimbine crosses the blood-brain barrier, producing both central and peripheral effects on the sympathetic nervous system. Each tablet contains 10 mg of yohimbine HCl. For laboratory research use only.
The Benefits of
Yohimbine
Yohimbine's primary area of research interest is its ability to enhance lipolysis by blocking alpha-2 adrenergic receptors in fat cells, particularly in stubborn adipose tissue where these receptors are highly concentrated. By elevating norepinephrine, it promotes fatty acid mobilization during fasted states and exercise. Research indicates improved peripheral circulation and oxygen delivery to tissue, increased energy expenditure, reduced fatigue, and enhanced endurance during physical activity. Studies using 0.2 mg/kg body weight have demonstrated increased fat oxidation without significant cardiovascular disruption in healthy subjects. At 10 mg per tablet, dosing is straightforward to titrate across research protocols. Its stimulatory effects on the sympathetic nervous system may also support motivation and exercise capacity.
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Canadian Made Labs’ Tablet Innovation
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